About Help FAQ

Symbol
Name
ID

Slc4a1
solute carrier family 4 (anion exchanger), member 1
MGI:109393

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Increased mean corpuscular hemoglobin concentration	Reticulocytosis	Anemia	Spontaneous hemolytic crises	Spherocytosis	Increased red cell osmotic fragility	Hypofibrinogenemia	Hypercoagulability	Extramedullary hematopoiesis	Splenomegaly
Disease(s) Associated with SLC4A1
hereditary spherocytosis

Mouse Phenotypes

enlarged spleen

abnormal definitive hematopoiesis

anemia

hemolytic anemia

macrocytic anemia

microcytic anemia

abnormal bone marrow cell number

absent erythroid progenitor cell

abnormal proerythroblast morphology

abnormal erythroblast morphology

abnormal erythrocyte morphology

abnormal erythrocyte cell number

decreased erythrocyte cell number

low mean erythrocyte cell number

decreased hematocrit

abnormal hemoglobin

decreased hemoglobin content

abnormal mean corpuscular hemoglobin

abnormal mean corpuscular volume

decreased mean corpuscular volume

increased mean corpuscular volume

increased nucleated erythrocyte cell number

hyperchromasia

microcytosis

poikilocytosis

polychromatophilia

spherocytosis

stomatocytosis

thrombocytopenia

reticulocytopenia

reticulocytosis

abnormal splenic cell ratio

hemolysis

increased erythrocyte osmotic fragility

Availability

Mouse Genotype

Slc4a1^l11Jus51/Slc4a1^l11Jus51

Slc4a1^tm1Ahc/Slc4a1^tm1Ahc

Slc4a1^tm1Dmb/Slc4a1^tm1Dmb

Slc4a1^tm1Llp/Slc4a1^tm1Llp

Slc4a1^tm1Phsl/Slc4a1^tm1Phsl

Slc4a1^wan/Slc4a1^wan

Slc4a1^tm1Llp/Slc4a1^wan

Slc4a1^tm1Phsl/Slc4a1⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23